How many of you feel Post Orgasmic Illness Disorder (POIS) is a rare disease?

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Postorgasmic illness syndrome (POIS) is a syndrome in which men have chronic physical and cognitive symptoms immediately following ejaculation in the absence of a local genital reaction. The symptoms last for up to a week . The cause and prevalence are unknown; it is considered a rare disease.

POIS

Symptoms :

The distinguishing characteristics of POIS are:

the rapid onset of symptoms after ejaculation;
the absence of any local genital reaction; and
the presence of an overwhelming systemic reaction.
POIS symptoms, which are called a "POIS attack", can include some combination of the following: cognitive dysfunction, aphasia, severe muscle pain throughout the body, severe fatigue, weakness, and flu-like or allergy-like symptoms,such as sneezing, itchy eyes, and nasal irritation. Additiona symptoms include headache, dizziness, lightheadedness, sensory and motor problems, intense discomfort, irritability, anxiety, gastrointestinal disturbances, craving for relief, susceptibility to nervous system stresses (e.g. common cold), depressed mood, and difficulty communicating, remembering words, reading and retaining information, concentrating, and socializing.Affected individuals may also experience intense warmth or cold.

The symptoms begin shortly after or within a half hour of ejaculation.

The symptoms can last for several days, sometimes up to a week.

In some men, the onset of POIS is in puberty, while in others, the onset is in their twenties.[medical citation needed] POIS that is manifest from the first ejaculations in adolescence is called primary type; POIS that starts later in life is called secondary type.

Many POIS sufferers report lifelong premature ejaculation, with intravaginal ejaculation latency time (IELT) of less than one minute.

Diagonosis :

diagnosis of POIS is based on the presence of the following criteria:]On or more associated symptoms
Symptoms develop within seconds or a short time after ejaculation
Symptoms always, or almost always, occur after ejaculation (after at least 90% of ejaculations)
Symptoms last for approximately 2 to 7 days
Symptoms resolve on their own within one week
The symptoms of POIS may be generalized, or may "cluster" in certain areas of the body (i.e. individual men report their symptoms only affect their head, eyes, nose, throat, or muscles). Reporting these clusters of symptoms may help with a diagnosis.[5]

One test that may be helpful for a diagnosis is a skin prick test, using a very diluted sample of the patient's own semen. This test needs a doctor's supervision because it can cause POIS symptoms and may result in a severe reaction requiring hospitalization.

Another test that may be helpful is advising the man to stop masturbating, or to stop having intercourse, just before the first genital sensations of impending

TREATMENT :

There is currently limited information available on the treatment and management of POIS. Some men with symptoms of POIS have been treated with SSRIs, antihistamines, and benzodiazepines.

One study used hyposensitization therapy to successfully treat two men with POIS. This type of therapy aims to decrease the immune response to an allergen by exposure. The men were inoculatedevery two weeks with increasing concentrations of their own semen. Although this therapy did not prevent symptoms entirely, both men reported a gradual improvement of symptoms over the treatment period. However, hyposensitization therapy may not be an option for all men with POIS, as it has been suggested that at least some cases of POIS may not be due to a semen allergy.