Is a sex change biologically impossible?

“’Sex change’ is biologically impossible. People who undergo sex-reassignment surgery do not change from men to women or vice versa. Rather, they become feminized men or masculinized women." - Dr. Paul R. McHugh
Is a sex change biologically impossible?



"The cold biological truth is that sex changes are impossible. Every single cell of the human body remains coded with one's birth gender for life. Intersex ambiguities can occur, but they are developmental anomalies that represent a tiny proportion of all human births." - Camille Paglia
Yes, a sex change is impossible
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No, it's possible. Someone can change from a man to a woman or vice versa
Vote B
I don't know
Vote C
I'm asexual
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Most Helpful Girls

  • Well, you can't change from XX to XY or vice versa, but we have advanced procedures in this day and age as far as appearance goes.

    • Yes please

  • Technically yes, but sex doesn't determine gender and neither are binary

    • So every female human being is not necessarily a woman?

    • Depends how you use the terms, like 'female' can describe gender or sex, it's confusing. But basically yeah, people assigned female at birth based on what they look like or chromosomes or whatever aren't necessarily girls and women, they could be boys and men or non binary people. And it's important to remember that not all trans people have surgery or want surgery; many are happy with their bodies but just not how society interprets their identities based on their bodies

    • A gender identity that was invented in Tumblr 10 years ago isn't proof that sex and gender don't correlate. This is was not a thing until a few years ago

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Most Helpful Guys

  • You can create the part but not the magic.

    • Me MHO please?

  • Yes, a sex change is impossible

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What Girls & Guys Said

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  • As a transgirl, I say -
    Well, duh.

    Transpeople are under no delusion that they have changed their biology.
    This is one of these weird strawmen that actually comes from the right wing, anti-trans crowd, not from within the trans community itself.
    (I know that there are crazy SJWs who might claim this, but using them as a common example is basically committing the right wing equivalent of Godwins Law.)

    It doesn't matter that my DNA is that of a males - It's all about looking the way I want to, and trying to ingratiate myself into my culture in a way that I think is more in-keeping with the way I want to be perceived. Biological change is indeed impossible, but the medical and cosmetic changes are the better choice, between this and just hating myself.
    If that isn't enough for someone to understand the motives behind transgenderism, then they'll never get it.

    • "Transpeople are under no delusion that they have changed their biology." So why do they so often lie about being what they are not? Where does this "If he loves me, he won't care that I used to be a man" crap come from?

    • @WalterRadio Ask someone who holds that opinion.

  • You cannot change your sex. Intersex is the only ambiguous sex. Everyone else is either male or female and cannot switch between the two. Similarly, we cannot become zebras.

  • You can't change yourself on a cellular level. Even if you graft a penis onto where your vagina used to be. I respect pronouns and all that, but the DNA doesn't lie, the hormones alone aren't a reliable indicator of sex (they merely cause traits typically associated with particular sexes), and the new genitalia isn't functional. Of course I'd never tell trans people they weren't valid or say this to their face, but we all know it's true

  • A gender change can be, you can't change everything but you can get close. My perspective is that I don't really care how people identify themselves, it doesn't affect me in any way.

  • Depends on how in depth specific you want to get with the term “sex change”. We all know what it means and most people with half a brain know that Caitlyn Jenner won’t be getting pregnant.

  • "I said B. I think that the argument posited by the two individuals quoted is a result of a gross conceptual error about what the discussion is about. The discussion is not about whether or not a persons chromosomal makeup can be changed, but whether or not they're hormones can be changed to make them look like more stereotypical males and females, and in extreme cases changes to their genitals to reflect the gender that they associate as. This is not about genetics, but about gender, hence the reason that they are called transGENDER."
    -BiDaddy

  • Depends if your asking specifically about humans or not

  • This doctor, who is a distinguished professor of psychiatry at Johns Hopkins, is right. Unethical surgeons might amputate a man's penis and pump him full of estrogen so that he grows breasts, but every cell in his body will still contain the Y-chromosome. And Dr. McHugh has been a passionate advocate for children not being subjected to these procedures. The so-called "transgender" ideology has become dangerous, and it's being pushed more and more on young children.

    • I agree 100%

  • A society that can put a man on the moon and explain superstition with science is advanced and civilized. A society that thinks you can summon the rain with dancing is primitive. Deal with it.

    Intersex is not a sex. It's a combination of male sex characteristics and female sex characteristics. You can't put Pikachu and Sonic the Hedgehog together and say "Hey, look, this is an entirely new and original character". It's just a mishmash of two original characters. And intersex people end up identifying as either male or female anyway.

  • Sex is ultimately determined by your chromosome. Which is as close to your DNA as it can get.

    Any biology student well tell you that you can't completely change a person DNA because they are coded into every cell. Even if you could somehow change every single cell in a person body, you will still have the nerves and the brain cells. You can't change brain cells without erasing the person.

    Now, there are genotype and phenotype. You can't change the genotype but you can change how the genes express themselves by changing the phenotype.

  • It is not possible no matter how hard a person who is a transgender try to convince themselves they changed their gender. If you added boobs , removed ur penis and taking hormone pills you are still a man you are just a mutated man thats it. you can't get pregnant nor can you have breast milk nor can you have periods. Accept the reality and grow up

  • Yes. Sex change is impossible.

    However that doesn't matter. Throughout human history, in all cultures and in all ages, there have always been a small number of people (usually men) who wanted to be/believed they were, the opposite sex.

    Depending on each society's particular beliefs, these people have been variously revered or killed. I am not a sociologist or an anthropologist, but I have read enough to know that this is true.

    The question is, in OUR society, how shall WE treat these people? Should we round them all up and kill them as was done in Nazi Germany? Should we revere them as being touched by a god as those supposedly touched by the goddess Cybele were in ancient Greece were?

    Personally, I don't have the heart to kill people who just want to act "funny" but I sure as hell am not going to worship any gods or goddesses.

    As an aside, I'd like to address a common objection that is often raised regarding transgendered people.

    "They're just crazy. They want to be something they're not." This is often followed by, "Well, if they can be something they're not (a woman or a man respectively) then I can be..." Followed by a list of silly objects or creatures and the humorous outcomes of that decision.

    This objection makes a lot of sense, at least at first glance, but not after you really think about it. I'll tell you why in my next installment.

    • First, although there are sporadic cases of people wanting to be dogs or cats or whatever, there are, and always have been, relatively large numbers of people who want to be the opposite sex.

      Secondly remember, ALL guys were once female in the womb, and all girls are just one small gene, the SRY Gene, away from being a guy.

      en.m.wikipedia.org/wiki/Testis-determining_factor

      Given these facts, it seems reasonable to assume that there's more going on here than meets the eye. There seems to be an ongoing tendency for a small proportion of the population to feel as though they "have the wrong body."

      I'm just guessing, but what if there is some gene or something that prepares a person's brain to be in a male body versus a female body? What if that process can get fucked up from time to time?

    • In any case, I'm getting ahead of myself. The truth is that there are these people. They think that they're in the wrong sex's body. We as a society have a choice, and it seems to me that enabling them to live their lives as close to changing their sex as they can, is the best choice. It must be miserable feeling like you should have a vagina when you've got a dick instead or vice versa.

    • In utero when the testes begin to drop they'll send some testosterone to the brain and functionally change it a bit. The hypothesis (which appears to have some validity) is that in transgendered males for whatever reason this does not occur.

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  • No it's not possible because genetics is genetics but if the small things done can help someone live in piece of mind and body why not let them

  • I don't know, I'm asexual.

  • I agree with that statement

  • @Sorathevilone Can you procreate like the opposite gender when changing it?

  • Yeah. In the future we might develop a technology capable at changing your dna at a cellular level that would make it be that way but its unlikely.

  • It's biologically impossible.

  • In my personal opinion, your gender is even in your DNA, and Brain... and those things are impossible to change.

  • No impossible, but with our current technology, not a complete change. Give it a decade or two and we could develop methods using DNA editing.

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